Erythritol triggers expression of virulence traits in Brucella melitensis
نویسندگان
چکیده
منابع مشابه
Isolation, cloning and expression of the Brucella melitensis Omp31 gene
Brucellosis is a zoonotic disease transmitted to humans either from animals or from their products.Although brucellosis can be found worldwide, the Mediterranean Basin, South and Central America, EasternEurope, Asia, Africa, the Caribbean, and the Middle East have currently been listed as high-risk regions. Thegenus Brucella is classified in at least nine species. Brucella melitensis is the glo...
متن کاملResponse of the vaccine strain of Brucella melitensis Rev I to erythritol.
The vaccine strain of Brucella mnelitensis designated as Rev I (M. Herzberg and S. S. 'Elberg, J. Bacteriol. 66:585, 1953; 69:432, 1955) and used in the protection of goats and sheep against brucellosis is characterized by slow colony development (4 to 5 days) on various solid media, increased sensitivity to penicillin (5 to 10 units), and increased resistance to streptomycin (5 ,ug) as contras...
متن کاملBrucella melitensis: a nasty bug with hidden credentials for virulence.
O September 23, 1905, a cargo carrying 60 goats from Malta arrived in New York. The herd was kept in quarantine because of several deaths that occurred during the journey. Crewmen, an agent from the U.S. Bureau of Animal Industry, which was responsible for the shipment, and a woman who drank milk that ‘‘escaped’’ from the quarantine station displayed the characteristic symptoms of ‘‘Mediterrane...
متن کاملIn silico cloning and bioinformatics study of Brucella melitensis Omp31 antigen in different mammalian expression vectors
Brucella melitensis, as a pathogenic gram-negative intracellular bacterium, causes brucellosis in animals and humans. According to literature, the B. melitensis outer membrane protein 31 (Omp31) is considered as an important vaccine candidate against brucellosis. The aim of the current study was to compare three different expression constructs containing B. melitensis Omp31 antigen using bioinf...
متن کاملPersister cells formation and expression of type II Toxin-Antitoxin system genes in Brucella melitensis (16M) and Brucella abortus (B19)
Background & Objective: Persister cells are defined as a subpopulation of bacteria that are capable of reducing their metabolism and switching to dormancy in stress conditions. Persister cells formation has been attributed to numerous mechanisms, including stringent response and Toxin-Antitoxin (TA) systems. This study aimed to investigate the hypothetical role of TA systems in...
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ژورنال
عنوان ژورنال: Microbes and Infection
سال: 2013
ISSN: 1286-4579
DOI: 10.1016/j.micinf.2013.02.002